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  • mProX™ Human NMUR1 Stable Cell Line

    [CAT#: S01YF-0923-PY132]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX660 Magic™ Mouse NMUR1 in Vitro IP1 Assay Mouse CHO-K1 IP1 Assay
    S01YF-1122-KX661 Magic™ Mouse NMUR1 in Vitro Radioligand Binding Assay Mouse CHO-K1 Radioligand Binding Assay

    Product Information

    Target Protein
    NMUR1
    Target Family
    Neuromedin U Family
    Target Protein Species
    Mouse
    Host Cell Type
    MC3T3-E1;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Immunology Research;Metabolic Research
    Related Diseases
    Spherocytosis, Type 3;Body Mass Index Quantitative Trait Locus 11
    Gene ID
    Mouse: 14767
    UniProt ID
    Mouse: O55040

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Neuromedin U receptor 1 (NMUR1) is a G-protein coupled receptor that is activated by the neuromedin U (NMU) peptide. This receptor is widely expressed in the central nervous system and has been implicated in various physiological processes, including the regulation of energy homeostasis, stress responses, and pain modulation. Recent studies have highlighted the potential of targeting NMUR1 for the treatment of obesity and metabolic disorders. Furthermore, the modulation of NMUR1 signaling has been suggested as a promising strategy for the treatment of neuropsychiatric disorders. The therapeutic potential of NMUR1 modulation offers exciting prospects for future research and drug development.

    Protocols

    Please visit our protocols page.

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    FAQ

    chat Sharon (Verified Customer)

    How is NMUR1 expression related to obesity and osteoarthritis? Nov 12 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    NMUR1 expression is found to be elevated in the synovial membrane of obese osteoarthritis patients. The increased NMUR1 expression in mast cells suggests a potential link between obesity and osteoarthritis pathology. Nov 12 2022

    chat Robert (Verified Customer)

    What is the significance of NMUR1 in the context of respiratory infections? Oct 17 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    During acute RSV infection, NMUR1 expression is up-regulated in the lungs, suggesting its role in the immune response and inflammation associated with respiratory infections. Oct 17 2022
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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