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    mProX™ Human MCHR2 Stable Cell Line

    [CAT#: S01YF-0923-PY114]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    MCHR2
    Target Family
    Melanin-concentrating Hormone Family
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Schizophrenia 4;Griscelli Syndrome, Type 3
    Gene ID
    Human: 84539
    UniProt ID
    Human: Q969V1

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    MCHR2, another receptor for melanin-concentrating hormone, has been implicated in various physiological and pathological processes. Notably, genetic variations in MCHR2 have been associated with conditions like Prader-Willi-like syndrome. A study found suggestible evidence for the involvement of duplications in MCHR2 in the pathogenesis of alopecia areata. Furthermore, MCHR2 has been investigated in the context of atypical depression, providing insights into its potential role in mood disorders.

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    FAQ

    chat Emily (Verified Customer)

    What is the association of MCHR2 with alopecia areata? Mar 09 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Duplications in MCHR2 have been suggested to be involved in the pathogenesis of alopecia areata, based on a genomewide analysis in a Central European cohort. Mar 09 2023

    chat Jason (Verified Customer)

    How does MCHR2 influence body mass index in psychiatric patients? Jan 13 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Genetic polymorphisms in MCHR2 and/or MCHR1-AS1 may have an influence on obesity in psychiatric patients and play a role in the pathophysiology of atypical depression. Jan 13 2021

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