mProX™ Human MAS1 Stable Cell Line

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

MAS1, or the Mas1 receptor, is a gene that has been studied in various fields of research. In the field of evolutionary biology, MAS1 has been investigated in the model genus Neurospora to understand the origin of new genes and their functions. It has been found that lineage-specific genes (LSGs) in Neurospora are often located adjacent to telomeres and are involved in diverse regulatory functions. In the field of dementia research, MAS1 has been studied in relation to the renin-angiotensin system (RAS) and its dysregulation in Alzheimer's disease. The expression of MAS1 and other RAS genes has been found to be altered in normal aging and dementia, providing insights into the role of RAS in these conditions. In the field of sports medicine, MAS1 has been investigated in high-performance athletes to identify genetic variants associated with athletic performance and musculoskeletal injury. Several SNPs in MAS1 have shown significant associations with performance and injury in athletes. In the field of reproductive health, MAS1 has been studied in the placenta of pre-eclampsia patients to understand its expression and biological function in trophoblast cells. The expression of MAS1 has been found to be reduced in pre-eclampsia, but it does not affect the function of trophoblast cells. Finally, in the field of ophthalmology, MAS1 has been studied in Mueller cells to investigate its response to angiotensin II under hyperglycemic or hypoxic conditions. The expression of MAS1 and other genes in the renin-angiotensin aldosterone system (RAAS) has been found to be altered in Mueller cells, suggesting their involvement in retinal diseases. Overall, MAS1 has been studied in various contexts to understand its role in gene evolution, disease pathogenesis, athletic performance, reproductive health, and retinal diseases.