mProX™ Human MAPK8 Stable Cell Line

[CAT#: S01YF-1123-KX274]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1179	Magic™ Human JNK1(MAPK8) in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

MAPK8

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Infectious Research; Metabolic Research

Related Diseases

Hepatitis C and Fatty Liver Disease. Among its related pathways are MyD88 dependent cascade initiated on endosome and Prolactin Signaling

Gene ID

5599

UniProt ID

P45983

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The MAPK8 gene in humans codes for the widely distributed enzyme mitogen-activated protein kinase 8, or JNK1. This gene codes for a protein that belongs to the JNK and MAP kinase families. Involved in a multitude of cellular activities, including development, transcription control, differentiation, proliferation, and differentiation, MAP kinases serve as an integrating point for various biochemical signals. This kinase controls immediate-early gene expression in response to cell stimuli by activating in response to different cell stimuli and targeting particular transcription factors. It is discovered that TNF-alpha-induced apoptosis requires the activation of this kinase. Additionally, UV radiation-induced apoptosis, which is believed to be connected to the cytochrome c-mediated cell death pathway. The customized MAPK8 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Sarah

I have purchased this MAPK8 overexpression cell line and all producing reliable results. Sep 06 2023

chat Verified Customer

chat Thomas

The mouse MAPK8 cell line is an excellent candidate for use in in vitro assays. Mar 27 2021

chat Verified Customer

FAQ

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