mProX™ Human MAP3K5 Stable Cell Line
[CAT#: S01YF-1123-KX295]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
MAP3K5
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Metabolic Research
Related Diseases
Fatty Liver Disease and Liver Disease. Among its related pathways are TNFR1 Pathway and 4-1BB Pathway
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Apoptosis signal-regulating kinase 1 (ASK1), often referred to as mitogen-activated protein kinase 5 (MAP3K5), is a component of the mitogen-activated protein kinase pathway and a member of the MAP kinase family. In response to a variety of stressors, including oxidative stress, endoplasmic reticulum stress, and calcium influx, it activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in a Raf-independent manner. It has been discovered that ASK1 is connected to rheumatoid arthritis, diabetes, cancer, cardiovascular, and neurological illnesses. The protein-coding MAP3K5 gene is situated at locus 6q22.33 on chromosome 6, and the resulting transcribed protein is 1,374 amino acids long and has 11 kinase subdomains. The customized MAP3K5 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Jennifer
The MAP3K5 cell line has proven valuable in various experimental setups.
Apr 07 2020
Verified Customer
Carol
I believe this is a simple, sensitive and effective MAP3K5 KO cell line.
Apr 10 2020
Verified Customer
FAQ
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