mProX™ Human MAP2K3 Stable Cell Line
[CAT#: S01YF-1123-KX289]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
MAP2K3
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
DLBCL; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Infectious Research
Related Diseases
Inhalation Anthrax and Cutaneous Anthrax. Among its related pathways are MyD88 dependent cascade initiated on endosome and Prolactin Signaling
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The human MAP2K3 gene encodes the enzyme dual specificity mitogen-activated protein kinase kinase 3. A dual specificity protein kinase that is a member of the MAP kinase kinase family is the protein that this gene encodes. Mitogenic and environmental stressors activate this kinase, which then takes part in the signaling cascade regulated by MAP kinase. By phosphorylating MAPK14/p38-MAPK, it activates it. Insulin has the ability to activate this kinase, which is required for the production of the glucose transporter. It is discovered that the expression of the RAS oncogene causes the active form of this kinase to accumulate. This activation of MAPK14 is constitutive and results in the oncogenic transformation of primary cells. The etiology of Yersinia pseudotuberculosis involves the suppression of this kinase. The customized MAP2K3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Kimberly
I recently utilized the mouse MAP2K3 cell line from Creative Biolabs. This cell line proved to be an exceptional targeting tool for my research.
Sep 07 2022
Verified Customer
Rebecca
The MAP2K3 cell line has been crucial in elucidating the receptor's role in various biological processes.
Nov 01 2021
Verified Customer
FAQ
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