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  • mProX™ Human LTB4R Stable Cell Line

    [CAT#: S01YF-0923-PY92]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
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    Product Information

    Target Protein
    LTB4R
    Target Family
    Leukotriene Family
    Target Protein Species
    Human
    Host Cell Type
    Caki1;ACHN;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Immunology Research
    Related Diseases
    Dirofilariasis;Cicatricial Entropion
    Gene ID
    Human: 1241
    UniProt ID
    Human: Q15722

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    LTB4R, or Leukotriene B4 receptor, has been identified as a significant player in various diseases. In the context of cancer, LTB4R has been found to regulate the proliferation and apoptosis of renal clear cell carcinoma cells by modulating the AKT/mTOR signaling pathway. Moreover, LTB4R has been recognized as a novel biomarker and independent prognostic indicator for Acute Myeloid Leukemia (AML), shedding light on the crosstalk of leukemogenesis signaling pathways involving tumor immunity and metabolism. Additionally, the expression of LTB4R has been associated with immune infiltrates, suggesting its potential as a prognostic biomarker in pan-cancer.

    Protocols

    Please visit our protocols page.

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    FAQ

    chat Rebecca (Verified Customer)

    Does LTB4R play a significant role in the development of membrane protein cell lines across various expression systems? Mar 02 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The provided articles do not specifically mention the role of LTB4R in the development of membrane protein cell lines. However, it's essential to understand that LTB4R is a specific receptor with potential implications in cellular processes. Mar 02 2021

    chat William (Verified Customer)

    Is LTB4R exclusively an outer membrane protein? Oct 11 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The provided articles do not categorize LTB4R as an outer membrane protein. It's essential to refer to specific research articles or studies to determine its exact cellular localization. Oct 11 2021
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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