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  • mProX™ Human KCNJ2 Stable Cell Line

    [CAT#: S01YF-1123-KX42]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    KCNJ2
    Target Family
    GIRK
    Target Protein Species
    Human
    Host Cell Type
    SCLC H69; H446; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    Cardiovascular Research; CNS Research
    Related Diseases
    Andersen Cardiodysrhythmic Periodic Paralysis; Short Qt Syndrome
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The KCNJ2 gene is a member of a broad gene family that codes for the production of potassium channels. Both cardiac muscle and muscles used for movement have active KCNJ2 protein-made channels. These channels are crucial to the pattern of muscular tensing and relaxation in skeletal muscle, which permits movement. The channels in the heart are responsible for replenishing the cardiac muscle following each beat in order to preserve a steady rhythm. Although their precise function in bone growth is unknown, channels made with the KCNJ2 protein may also be involved in this process. Scientists have discovered that for channels produced with the KCNJ2 protein to operate properly, a molecule known as PIP2 needs to connect to the channel. The customized KCNJ2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Linda

    I purchased the KCNJ2 cell line. Hope it will work well. Apr 01 2022

    chat Verified Customer

    chat Cynthia

    I was so pleased with the KCNJ2 cell line I received from this business. Apr 09 2022

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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