mProX™ Human KCNH2 Stable Cell Line
[CAT#: S01YF-1123-KX35]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Ion Channel Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The KCNH2 gene is a member of a sizable gene family that codes for the production of potassium channels. Heart muscle contains active channels that are formed using KCNH2 proteins, also referred to as hERG1. In order to keep the heartbeat regular, they are involved in replenishing the cardiac muscle after each beat. In the brain and spinal cord, nerve cells as well as some immune cells generate the KCNH2 protein. Together, the proteins derived from the KCNH2 and KCNE2 genes construct a functioning potassium channel. The KCNH2 gene produces four alpha subunits, which together make up each channel's structure. The KCNE2 gene produces a single beta subunit that binds to the channel and controls its activity. The customized KCNH2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Brian
The KCNH2 cell line can be used as model systems to investigate fundamental aspects of cell biology and biochemistry.
Mar 30 2022
Verified Customer
Sharon
The KCNH2 cell line was exactly what I was looking for.
Jun 26 2021
Verified Customer
FAQ
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