mProX™ Human KCND3 Stable Cell Line
[CAT#: S01YF-1123-KX29]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Ion Channel Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The protein known as Kv4.3, or potassium voltage-gated channel subfamily D member 3, is encoded by the KCND3 gene in humans. It is a component of the cardiac transient outward potassium current, which is the primary current that contributes to the ventricular action potential's repolarizing phase 1. Kv4.3 belongs to the voltage-gated, shal-related subfamily of potassium channels, which is known for producing voltage-activated A-type potassium ion channels and being highly active during the action potential's repolarization phase. This gene has two isoforms that differ in size; these isoforms are produced by transcript variants that splice differently. Brugada syndrome is thought to be caused by gain of function, but this is only partially demonstrated by mutations in the beta subunit KCNE3, which results in gain of function of Kv4.3. The customized KCND3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Brian
I purchased the Human KCND3 Stable Cell Line hoping it would meet my project requirements.
Mar 04 2022
Verified Customer
Melissa
This KCND3 cell line is unparalleled performance and quality.
Dec 10 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
