mProX™ Human KCNC4 Stable Cell Line

[CAT#: S01YF-1123-KX27]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Ion Channel Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

KCNC4

Target Family

Kv3

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Ion Channel Cell Lines

Target Research Area

Cardiovascular Research; CNS Research

Related Diseases

Congenital Disorder Of Glycosylation; Spinocerebellar Ataxia

Gene ID

3749

UniProt ID

Q03721

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Kv3.4, also known as potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), is a gene found in humans. There are four subfamilies within the Drosophila Shaker gene family, which encodes voltage-gated potassium channel components. This gene is similar to the Shaw subfamily based on sequence similarities. The protein that this gene encodes is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It is a member of the delayed rectifier class of channel proteins. It produces an unusual transient voltage-dependent current, which could be crucial for the excitability of neurons. For this gene, several transcript variants encoding distinct isoforms have been discovered. The customized KCNC4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

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