mProX™ Human INSR Stable Cell Line
[CAT#: S01YF-1123-KX266]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
INSR
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Diabetes Research
Related Diseases
Donohue Syndrome and Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities. Among its related pathways are GPCR Pathway and ERK Signaling
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The INSR gene codes for the production of an insulin receptor protein, which is present in a variety of cell types. Insulin receptors bind to the insulin hormone that circulates in the bloodstream and are implanted in the outer membrane of the cell. When the insulin receptor is first made, it is a single, lengthy protein that needs to be divided into two alpha and two beta subunits in order to be processed. Together, these subunits form a functional receptor. While the beta subunits stay inside the cell, the alpha subunits protrude from the cell's surface. When the alpha subunits bind to insulin, the beta subunits initiate cellular signaling pathways that affect a variety of cellular processes. The customized INSR stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Brian
I recently had the opportunity to try the INSR KD cell line from Creative Biolabs, and I am quite impressed.
Apr 09 2022
Verified Customer
Sharon
I can't speak highly enough about the human INSR cell line. It has exceeded my expectations in terms of performance.
Mar 10 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
