Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. HTR2B
  3. mProX™ Human HTR2B Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP GPCR Cell Lines,Drug Discovery Tools
    Family stable cell lines 5-Hydroxytryptamine Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human HTR2B Stable Cell Line

    [CAT#: S01YF-0923-KX35]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX924 Magic™ Rat HTR2B in Vitro Calcium Flux Assay Rat CHO-K1 Calcium Flux Assay
    S01YF-1122-KX925 Magic™ Rat HTR2B in Vitro IP1 Assay Rat CHO-K1 IP1 Assay

    Product Information

    Target Protein
    HTR2B
    Target Family
    5-Hydroxytryptamine Family
    Target Protein Species
    Human
    Host Cell Type
    T108; CHO-K1; HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research; Cardiovascular Research
    Related Diseases
    Ocular Hypotension; Heart Valve Disease
    Gene ID
    3357
    UniProt ID
    P41595

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    HTR2B mediates the activation of alternative signaling pathways while suppressing G protein-mediated signaling. Neural activity is impacted by 5-HT2B because it controls dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine absorption, and extracellular dopamine and 5-hydroxytryptamine levels. Additionally, 5-HT2B affects how behavior, notably impulsive conduct, is regulated. It is necessary for healthy heart development and appropriate embryonic cardiac myocyte proliferation. Additionally, it helps defend cardiomyocytes from apoptosis. Additionally, 5-HT2B contributes to vasoconstriction and the adaptation of the pulmonary arteries to chronic hypoxia. Recently developed 5-HT2B receptor antagonists may be useful for treating migraines due to the 5-HT2B receptor's vasodilatory function. The customized HTR2B stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human HTR2B Stable Cell Line (S01YF-0923-KX35). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Edison (Verified Customer)

    Can the HTR2B cell line be used in protein-protein interaction studies? Oct 18 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Yes, cell lines expressing specific proteins can be used in protein-protein interaction studies to understand the function and interaction partners of the protein of interest. Oct 18 2022

    chat Pandora (Verified Customer)

    How is the stability of the HTR2B protein ensured in the stable cell line? Apr 16 2023

    chat Sherry Smith (Creative Biolabs Scientific Support)

    The stability of the HTR2B protein is ensured through the use of specific cell culture conditions and the selection of cells that stably express the HTR2B protein. Apr 16 2023

    Related Products by Target
    • Magic™ Human FLAG tagged HTR2B CHO-K1 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX593)
    • Magic™ Human FLAG tagged HTR2B HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX594)
    • Magic™ mPro Mouse HTR2B Cell Line (CAT#: S01YF-1122-KX60)
    • Magic™ Mouse FLAG tagged HTR2B HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX595)
    • Magic™ Human HTR2B CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay (CAT#: S01YF-1222-KX264)
    • Magic™ Human 5-HT2B CHO-K1 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX3)
    • mProX™ Human HTR2B Stable Cell Line (CAT#: S01YF-0923-KX35)
    • Magic™ mPro Human 5-HT2B Cell Line (CAT#: S01YF-1122-KX2)
    • Magic™ Human HTR2B CHO-K1 Cell Line, Binding and Functional Assay (CAT#: S01YF-1222-KX265)
    • Magic™ Human HTR2B CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay (CAT#: S01YF-1222-KX121)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare