mProX™ Human HCN2 Stable Cell Line

[CAT#: S01YF-1123-KX85]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Ion Channel Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

HCN2

Target Family

Hyperpolarization-activated, Cyclic Nucleotide-gated Channels

Target Protein Species

Human

Host Cell Type

PC12; CHO-K1; HEK293

Target Classification

Ion Channel Cell Lines

Target Research Area

Cardiovascular Research; CNS Research

Related Diseases

Epilepsy; Idiopathic Generalized; Febrile Seizures

Gene ID

610

UniProt ID

Q9UL51

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Humans' HCN2 gene codes for a protein known as potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2. Although the channel's activation by hyperpolarization suggests the funny channels in the heart's sinoatrial node-which are the source of spontaneous electrical rhythm generation-its exact function is unknown. Blocking the gene is linked to the resolution of neuropathic pain episodes, and these channels have recently been linked to chronic pain. The customized HCN2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Richard

The HCN2 cell line worked as advertised and was a cost-effective alternative in our studies. We obtained consistent results, and the cell line showed good stability over extended periods. Dec 02 2022

chat Verified Customer

chat Timothy

The HCN2 cell line worked flawlessly, and the detailed protocols provided by the company made the whole process much easier. Oct 26 2021

chat Verified Customer

FAQ

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