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    Family stable cell lines Metabotropic Glutamate Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human GRM6 Stable Cell Line

    [CAT#: S01YF-0923-PY124]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    GRM6
    Target Family
    Metabotropic Glutamate Family
    Target Protein Species
    Human
    Host Cell Type
    ;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Ocular Research
    Related Diseases
    Night Blindness, Congenital Stationary, Type 1B;Congenital Stationary Night Blindness
    Gene ID
    Human: 2916
    UniProt ID
    Human: O15303

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GRM6 encodes the metabotropic glutamate receptor 6 (mGluR6), which plays a significant role in the retina, particularly in the transmission of visual signals. Mutations in GRM6 have been linked to congenital stationary night blindness, a condition that affects vision in low light conditions. The receptor is involved in the signaling from retinal rod cells to ON-bipolar cells, and any disruption in this pathway can impair vision in dim light.

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    FAQ

    chat Michael (Verified Customer)

    What is the significance of GRM6 in vision? Apr 22 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GRM6 is associated with congenital stationary night blindness, which affects vision in low light conditions due to alterations in GRM6 binding and signaling from the retinal rod cell to the ON-bipolar cell. Apr 22 2020

    chat Sarah (Verified Customer)

    What is the function of the GRM6 gene? Aug 05 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The GRM6 gene provides instructions for making a protein called metabotropic glutamate receptor 6 (mGluR6), which is a type of protein that binds to the signaling molecule glutamate on the surface of cells. Aug 05 2023

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    • mProX™ Human GRM6 Stable Cell Line (CAT#: S01YF-0923-PY124)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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