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    Family stable cell lines Glutamate Receptor Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human GRIN1/GRIN2D Stable Cell Line

    [CAT#: S01YF-1123-KX73]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Product Information

    Target Protein
    GRIN1/GRIN2D
    Target Family
    Glutamate Receptor
    Target Protein Species
    Human
    Host Cell Type
    SW1990; PANC04.03; PANC1; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Neurodevelopmental Disorder
    Gene ID
    2902
    UniProt ID
    Q05586

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The human GRIN2D gene encodes the protein glutamate [NMDA] receptor subunit epsilon-4. Ionotropic glutamate receptors include the N-methyl-D-aspartate (NMDA) receptor class. Long-term potentiation, an activity-dependent improvement in synaptic transmission efficiency believed to underpin some forms of memory and learning, has been linked to the NMDA channel. The main receptor subunit NMDAR1 (GRIN1) and one or more of the four NMDAR2 subunits-NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D)-compose heteromers that make up NMDA receptor channels. The customized GRIN1/GRIN2D stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human GRIN1/GRIN2D Stable Cell Line (S01YF-1123-KX73). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Jessica (Verified Customer)

    Are there any known roles of GRIN1/GRIN2D in programmed cell death? Aug 10 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Direct associations between GRIN1/GRIN2D and programmed cell death aren't explicitly mentioned. Aug 10 2022

    chat Michael (Verified Customer)

    What are the potential applications of GRIN1/GRIN2D in tumor cell line research? Apr 22 2020

    chat Sherry Smith (Creative Biolabs Scientific Support)

    While the direct applications of GRIN1/GRIN2D in tumor cell line research aren't specified in the provided articles, extracellular vesicles from certain cell lines have shown broad and potent anti-tumor activity. Apr 22 2020

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    • mProX™ Human GRIN1/GRIN2D Stable Cell Line (CAT#: S01YF-1123-KX73)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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