mProX™ Human GRIA1 Stable Cell Line

[CAT#: S01YF-1123-KX74]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Ion Channel Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

GRIA1

Target Family

Glutamate Receptor

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Ion Channel Cell Lines

Target Research Area

CNS Research

Related Diseases

Alacrima; Achalasia; Mental Retardation Syndrome; Depression.

Gene ID

2890

UniProt ID

P42261

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The GRIA1 gene in humans encodes the protein glutamate receptor 1. Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors include the GRIA1 receptor. Alternative RNA splicing produces flip and flop isoforms in each of the members (GRIA1-4). Each variant encodes a different receptor subunit, with different signal transduction characteristics. The flop isoform is the one that is being shown here. Human GRIA1 mRNA was found to be present in the granule and pyramidal cells of the hippocampus formation by in situ hybridization tests. The primary factor influencing synaptic plasticity is GRIA1 (GluR1). The human frontal brain has a considerable decrease in GluR1 gene expression as one ages. The customized GRIA1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Kimberly

The GRIA1 cell line has played a pivotal role in our journey of discovery. Its reliable performance and consistent results have propelled our research forward. Sep 19 2021

chat Verified Customer

chat Michael

I've used the GRIA1 KO cell line in multiple assays, and each time, it has exceeded my expectations. Jan 03 2023

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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