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    mProX™ Human GPR85 Stable Cell Line

    [CAT#: S01YF-0923-PY168]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GPR85
    Target Family
    Orphan Family
    Target Protein Species
    Human
    Host Cell Type
    NAF6;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Gene ID
    Human: 54329
    UniProt ID
    Human: P60893

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GPR85, also known as SREB2, has been recognized for its role in brain function and behavior. It has been associated with the regulation of brain size and has been suggested to influence vulnerability to schizophrenia. GPR85's involvement in the modulation of cAMP levels in T cells has been explored, but its role in encephalitogenic responses appears to be minimal. Additionally, GPR85 has been linked to the regulation of hippocampal adult neurogenesis, which impacts cognitive function.

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    FAQ

    chat Lisa (Verified Customer)

    What is the significance of GPR85 in brain development? Jan 01 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPR85 is implicated in brain development and function. It's overexpression leads to an enlarged brain size, while its deletion results in a small brain, emphasizing its role in regulating brain size​. Jan 01 2022

    chat Nancy (Verified Customer)

    How is GPR85 related to neuropsychiatric disorders? Jan 27 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The expression level of GPR85 may be associated with neuropsychiatric disorders. It has been studied in the context of schizophrenia, and it could be a potential therapeutic target for neuropsychiatric disorders due to its role in brain development​​. Jan 27 2023

    Related Products by Target
    • Magic™ Human FLAG tagged GPR85 HEK293T Cell Line (CAT#: S01YF-1022-KX524)
    • mProX™ Human GPR85 Stable Cell Line (CAT#: S01YF-0923-PY168)
    • Magic™ Human FLAG tagged GPR85 CHO-K1 Cell Line (CAT#: S01YF-1022-KX525)
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