Recommended
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
  • mProX™ Human GPR84 Stable Cell Line

    [CAT#: S01YF-0923-PY198]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX470 Magic™ Rat GPR84 in Vitro Calcium Flux Assay Rat CHO-K1-Gqi5 Calcium Flux Assay
    S01YF-1122-KX471 Magic™ Rat GPR84 in Vitro cAMP Assay Rat CHO-K1 cAMP Assay

    Product Information

    Target Protein
    GPR84
    Target Family
    Orphan Family
    Target Protein Species
    Mouse
    Host Cell Type
    MH-S;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Alzheimer Disease 14
    Gene ID
    Mouse: 80910
    UniProt ID
    Mouse: Q8CIM5

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GPR84 is a medium-chain fatty acid receptor that plays a role in various physiological processes, including immune responses. It's been speculated that modulators of GPR84 might have applications in boosting cancer immunotherapies. Additionally, GPR84 has been associated with inflammatory responses in the gut, suggesting its potential role in conditions like ulcerative colitis. Another intriguing aspect of GPR84 is its involvement in brown adipocyte function, which has implications for metabolic diseases. Given its diverse roles, GPR84 is a promising target for drug development in various therapeutic areas.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human GPR84 Stable Cell Line (S01YF-0923-PY198). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Paul (Verified Customer)

    What is the association between GPR84 and inflammation? Apr 20 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPR84 plays a significant role in mediating inflammatory responses. For instance, GPR84 signaling can promote intestinal mucosal inflammation by enhancing the activation of the NLRP3 inflammasome in macrophages. Apr 20 2020

    chat Sharon (Verified Customer)

    How does GPR84 influence metabolic processes? Jan 06 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPR84 is involved in sensing energy load via nutrient exposure. It plays a key role as a nutrient-sensing GPCR in metabolism, indicating its potential role in metabolic disorders. Jan 06 2020
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare