mProX™ Human GPR83 Stable Cell Line

[CAT#: S01YF-0923-PY196]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Lot Number

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX791	Magic™ Mouse GPR83 in Vitro Calcium Flux Assay	Mouse	CHO-K1-Gα16	Calcium Flux Assay
S01YF-1122-KX792	Magic™ Mouse GPR83 in Vitro IP1 Assay	Mouse	CHO-K1-Gα16	IP1 Assay

Product Information

Target Protein

GPR83

Target Family

Orphan Family

Target Protein Species

Mouse

Host Cell Type

Neuro2A;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Gene ID

Mouse: 14608

UniProt ID

Mouse: P30731

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

GPR83, also known as the glucocorticoid-induced receptor, has been implicated in several physiological processes. It's been associated with immune system regulation, especially in T-cell function. This receptor has been studied for its potential role in autoimmune diseases, where the immune system mistakenly attacks the body's cells. Understanding the signaling pathways and ligands of GPR83 can provide insights into the development of targeted therapies for autoimmune disorders and other conditions where the immune response is dysregulated.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Cynthia (Verified Customer)

What is the role of GPR83 in the immune system? Oct 21 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

GPR83 is a multifunctional protein involved in various immune responses, including T cell regulation. It is expressed in several immune cells and plays a role in the differentiation of T helper cells. Targeting GPR83 might offer therapeutic potential for autoimmune diseases. Oct 21 2021

chat Robert (Verified Customer)

How does GPR83 influence energy homeostasis? Jun 09 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

GPR83 is expressed in the hypothalamus, a region critical for energy balance. It can influence energy homeostasis by affecting food intake and energy expenditure, making it a potential target for obesity-related research. Jun 09 2021

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