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    mProX™ Human GPR32 Stable Cell Line

    [CAT#: S01YF-0923-PY189]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GPR32
    Target Family
    Orphan Family
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Gene ID
    Human: 2854
    UniProt ID
    Human: O75388

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GPR32 has been identified as a receptor for resolvin D1, a molecule known to regulate the resolution of inflammation. This receptor's activation has been linked to atheroprotection, suggesting its potential role in cardiovascular health. Furthermore, studies have shown that GPR32 can modulate inflammatory responses, emphasizing its significance in conditions like sepsis and other inflammatory diseases. The receptor's ability to influence macrophage behavior further highlights its potential therapeutic implications.

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    FAQ

    chat Helen (Verified Customer)

    What is the function of GPR32 in cellular signaling? Sep 13 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPR32, known as G protein-coupled receptor 32 or the RvD1 receptor, is a seven-transmembrane G protein-coupled orphan receptor. It specifically interacts with Resolvin D1 (RvD1) and Lipoxin A4, playing a role in resolving acute inflammation. The interactions of GPR32 with these ligands suggest its involvement in inflammatory resolution processes, which can be crucial for studying inflammatory diseases and developing potential therapeutic strategies​. Sep 13 2022

    chat Michelle (Verified Customer)

    What are the potential applications of GPR32 custom cell line products in research? Mar 01 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPR32 custom cell line products can serve as invaluable tools in understanding the molecular mechanisms underlying inflammation resolution. They can be used to study the receptor's signaling pathways, ligand interactions, and its role in various inflammatory conditions. Additionally, these custom cell lines can facilitate drug discovery efforts aimed at identifying new anti-inflammatory agents or therapies that modulate GPR32 activity, which could be beneficial in treating a range of inflammatory diseases​​. Mar 01 2021

    Related Products by Target
    • mProX™ Human GPR32 Stable Cell Line (CAT#: S01YF-0923-PY189)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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