mProX™ Human GPR176 Stable Cell Line

[CAT#: S01YF-0923-PY179]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

GPR176

Target Family

Orphan Family

Target Protein Species

Human

Host Cell Type

DLD-1;HCT116;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research

Related Diseases

Narcolepsy

Gene ID

Human: 11245

UniProt ID

Human: Q14439

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

GPR176 is a G-protein coupled receptor that has garnered attention in the scientific community due to its potential role in the regulation of circadian rhythms. Recent studies have shown that GPR176 might act as a molecular clock in the suprachiasmatic nucleus, the primary circadian pacemaker in mammals. Its involvement in timekeeping mechanisms suggests that GPR176 could play a crucial role in maintaining the body's internal rhythm, influencing processes like sleep, metabolism, and hormone secretion6. Understanding the intricacies of GPR176's function could provide insights into the treatment of circadian rhythm disorders and other related conditions.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat William (Verified Customer)

What is the potential correlation between GPR176 and cancer? Jul 28 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

Research suggests that GPR176 may be a potential target gene in gastric cancer, with implications for immune cell infiltration in the tumor microenvironment. Jul 28 2020

chat Amanda (Verified Customer)

How does GPR176 influence circadian behaviors? Jan 19 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

GPR176 is a Gz-linked orphan G-protein-coupled receptor that has been associated with the regulation of circadian behaviors, acting as a pacemaker to maintain circadian rhythms. Jan 19 2020

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