mProX™ Human GPR142 Stable Cell Line

[CAT#: S01YF-0923-PY169]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX763	Magic™ Mouse GPR142 in Vitro IP1 Assay	Mouse	HEK293	IP1 Assay
S01YF-1122-KX764	Magic™ Rat GPR142 in Vitro IP1 Assay	Rat	HEK293	IP1 Assay

Product Information

Target Protein

GPR142

Target Family

Orphan Family

Target Protein Species

Rat

Host Cell Type

INS-1832/13;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Gene ID

Rat: 501735

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

GPR142 has been identified as a receptor that plays a role in metabolic regulation. It has been shown to influence glucose-dependent insulin secretion and has potential therapeutic implications for type 2 diabetes. The receptor's activation by aromatic amino acids has been explored, suggesting its role as a sensor for these molecules in metabolic processes. Additionally, GPR142 agonists have demonstrated anti-diabetic benefits in pre-clinical studies, highlighting their potential for clinical application.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Elizabeth (Verified Customer)

What is the therapeutic potential of GPR142? Nov 04 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

GPR142 is explored as a therapeutic target for type 2 diabetes due to its insulin secretagogue activity which stimulates glucose-dependent insulin secretion, indicating its potential in glucose homeostasis management. Nov 04 2022

chat Robert (Verified Customer)

How can GPR142 stable cell lines be utilized? Jun 16 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

Stable cell lines expressing GPR142 are used in functional genomics research and drug discovery studies. They are pivotal for investigating GPR142 signaling pathways and developing agonists for potential diabetes treatment. Jun 16 2023

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