Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. GDF15
  3. mProX™ Human GDF15 Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP Other Cell Lines,Drug Discovery Tools

    mProX™ Human GDF15 Stable Cell Line

    [CAT#: S01YF-1023-PY272]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;HeLa;HT-3
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    Cardiovascular Research
    Related Diseases
    Heart Disease; Colorectal Cancer
    Gene ID
    Human:9518
    UniProt ID
    Human:Q99988

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Growth differentiation factor 15 (GDF15) has various applications in different fields. In the context of systemic sclerosis (SSc), GDF15 is implicated as a biomarker and potential therapeutic target due to its involvement in the fibrotic process of SSc. In older men undergoing resistance training, soy milk ingestion along with resistance training resulted in significant changes in muscular-related biomarkers, including GDF15, indicating its role in muscle mass, strength, and power. In patients with osteoarthritis (OA), GDF15 is identified as one of the characteristic genes associated with apoptosis and OA development. Additionally, GDF15 is found to be elevated in patients with Helicobacter pylori (HP) infection, suggesting a correlation between GDF15 levels and subclinical atherosclerosis. In mesangial cells, GDF15 interference regulates proliferation, inflammation, and autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway. Overall, GDF15 has potential applications in the diagnosis, treatment, and understanding of various diseases and conditions.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human GDF15 Stable Cell Line (S01YF-1023-PY272). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Alex Johnson (Verified Customer)

    Does GDF15 play a role in normal erythroid differentiation? Jun 18 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GDF15 is essential in normal erythropoiesis and in the ineffective erythroid differentiation of patients with refractory anaemia with ring-sideroblasts, suggesting its significant role in erythroid development. Jun 18 2021

    chat Taylor Miller (Verified Customer)

    Can GDF15 influence mitochondrial membrane potential and antioxidant gene expression? Jul 31 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GDF15 enhances mitochondrial membrane potential and upregulates antioxidant genes, potentially improving embryo viability and implantation potential in mouse blastocysts cultured under low oxygen tension. Jul 31 2023

    Related Products by Target
    • Magic™ Human GDF15 CT26 Cell Line (CAT#: S01YF-0123-KX84)
    • Magic™ Human GDF15 MC-38 Cell Line (CAT#: S01YF-0123-KX85)
    • mProX™ Human GDF15 Stable Cell Line (CAT#: S01YF-1023-PY272)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare