mProX™ Human GABRA3 Stable Cell Line

[CAT#: S01YF-1123-KX66]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Ion Channel Cell Lines

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Lot Number

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Product Information

Target Protein

GABRA3

Target Family

GABAA

Target Protein Species

Human

Host Cell Type

SKBR3; MDA-MB-453; MDA-MB-436; MDA-MB-231; CHO-K1; HEK293

Target Classification

Ion Channel Cell Lines

Target Research Area

CNS Research

Related Diseases

Thyrotoxic Periodic Paralysis; Anxiety

Gene ID

2556

UniProt ID

P34903

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The GABRA3 gene in humans codes for the protein known as gamma-aminobutyric acid receptor subunit alpha-3. In the mammalian brain, GABA is the primary inhibitory neurotransmitter that operates through ligand-gated chloride channels called GABAA receptors. Benzodiazepines are among the drugs that can alter the chloride conductance of these channels by binding to the GABAA receptor. It has been determined that GABA-A receptors have at least 16 different subunits. The extracellular ligand binding domains and membrane-integrated ion channel domains make up the five subunits that make up GABA receptors. When ligands attach to these receptors, the channel gets activated. The customized GABRA3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Anthony

The prices are unbeatable, and the selection is great. Nov 01 2021

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chat Christopher

The Human GABRA3 Stable Cell Line is so great! Mar 03 2021

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