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    Family stable cell lines N-formylpeptide Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human FPR2 Stable Cell Line

    [CAT#: S01YF-0923-PY146]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX428 Magic™ Rat FPR2 in Vitro cAMP Assay Rat CHO-K1 cAMP Assay

    Product Information

    Target Protein
    FPR2
    Target Family
    N-formylpeptide Family
    Target Protein Species
    Human
    Host Cell Type
    SGC7901;XN0422;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Infectious Research;CNS Research
    Related Diseases
    Prion Disease and Diamond-Blackfan Anemia 2
    Gene ID
    Human: 2358
    UniProt ID
    Human: P25090

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    FPR2, another member of the formyl peptide receptor family, has been identified to have diverse roles in health and disease. Recent research has highlighted its involvement in the recognition of Aβ42, a peptide implicated in Alzheimer's disease, suggesting a potential therapeutic target for neurodegenerative conditions. Additionally, FPR2's role in modulating the inflammatory response has been explored in various contexts, from cerebral ischemia-reperfusion injury to the resolution of inflammation in sickle cell disease. The versatility of FPR2 in regulating both neural and immune processes underscores its significance in translational research.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human FPR2 Stable Cell Line (S01YF-0923-PY146). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Matthew (Verified Customer)

    How do formylpeptide receptors FPR1 and FPR2 recognize formyl peptides and synthetic agonists? Dec 22 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Formylpeptide receptors FPR1 and FPR2 recognize formyl peptides and synthetic agonists through specific cryo-EM structures, revealing a distinctive receptor activation mechanism. Dec 22 2022

    chat Kevin (Verified Customer)

    What is the role of FPR2 in the recognition of Aβ42 and neuroprotection by humanin? Aug 31 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FPR2 has critical regions that govern the recognition and activity of Aβ42 and humanin, including a polar binding cavity within the receptor helical bundle and a hydrophobic binding groove in the extracellular region. Aug 31 2020

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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