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  • mProX™ Human FPR1 Stable Cell Line

    [CAT#: S01YF-0923-PY145]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
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    Product Information

    Target Protein
    FPR1
    Target Family
    N-formylpeptide Family
    Target Protein Species
    Human
    Host Cell Type
    SiHa;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Infectious Research;Digestive and Renal Research
    Related Diseases
    Susceptibility To Localized Juvenile Periodontitis;Plague
    Gene ID
    Human: 2357
    UniProt ID
    Human: P21462

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    FPR1 is a member of the formyl peptide receptor family, which plays a critical role in the immune response, particularly in the chemotaxis of leukocytes. Recent studies have unveiled the structural intricacies of how FPR1 recognizes formyl peptides and synthetic agonists, shedding light on its function as a pattern recognition receptor. This understanding can be instrumental in devising therapeutic strategies targeting inflammatory conditions, where the immune response is either exacerbated or diminished. The potential to modulate the immune response via FPR1 can have profound implications in conditions ranging from autoimmune diseases to cancer.

    Protocols

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    Customer Reviews

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    FAQ

    chat Rebecca (Verified Customer)

    How does FPR1 influence cell line growth and motility? May 04 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FPR1 can impact cell line growth and motility, potentially by regulating pathways like the FAK pathway. May 04 2022

    chat Timothy (Verified Customer)

    Are there specific cell lines where FPR1 expression is prominent? Aug 21 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FPR1 expression can be observed in various cell lines, including breast cancer cells, where it has been linked to proliferation and migration behaviors. Aug 21 2022
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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