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    mProX™ Human FOLH1 Stable Cell Line

    [CAT#: S01YF-1023-PY270]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;LNCap
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    Metabolic Research
    Related Diseases
    Hyperhomocysteinemia; Prostate Cancer
    Gene ID
    Human:2346
    UniProt ID
    Human:Q04609

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    FOLH1, also known as prostate-specific membrane antigen (PSMA), has various applications in different fields. In cancer research, FOLH1 has been used as a target for imaging agents in prostate-specific membrane antigen inhibitor studies. It has also been studied in relation to genetic polymorphisms and arsenic methylation efficiency during pregnancy. Additionally, FOLH1 has been compared to other imaging techniques, such as 18F-FDG PET/CT, in evaluating patients with upper tract urothelial carcinoma. Furthermore, FOLH1 expression has been examined in the neovasculature of high-grade gliomas, suggesting its potential role in tumor angiogenesis. Finally, scRNA-seq analysis has revealed the heterogeneity of the tumor microenvironment related to lymph node metastasis in prostate cancer, with FOLH1 being identified as a marker in luminal cell subgroups. These findings highlight the diverse applications and significance of FOLH1 in different research areas.

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    FAQ

    chat Skyler Johnson (Verified Customer)

    How is FOLH1/PSMA regulated in prostate cancer? Mar 20 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FOLH1 is regulated by epigenetic control and may be altered in progression or with androgen deprivation therapy, suggesting a complex regulatory mechanism in prostate cancer. Mar 20 2021

    chat Alex Garcia (Verified Customer)

    Can FOLH1 expression be used for diagnostic imaging in cancers? Jun 18 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FOLH1 (PSMA) expression in hepatocellular carcinoma and other tumor types suggests its potential use for prognosis and diagnostic imaging. Jun 18 2022

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    • mProX™ Human FOLH1 Stable Cell Line (CAT#: S01YF-1023-PY270)
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