mProX™ Human FOLH1 Stable Cell Line
- Product Category:
- Membrane Protein Stable Cell Lines
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Published Data
Fig.1 The attenuation of LNCaP cell proliferation was observed following the knockdown of PSMA.
Cell viability was assessed through the utilization of the CCK-8 assay, with absorbance at 450 nm being employed to measure the protracted cell growth curve. Within the normal medium, it was observed that the interference group exhibited a lower proliferative capacity compared to both the blank group and the non-interference group, with the maximum inhibition rate being reached at the 120-hour mark. In the medium containing LY2**002, cells were found to possess proliferative capacities at diminished levels. The data presented here represent the mean ± SD of a representative experiment conducted in triplicate (n=3).
Ref: Guo, Zhenghui, et al. "Prostate specific membrane antigen knockdown impairs the tumorigenicity of LNCaP prostate cancer cells by inhibiting the phosphatidylinositol 3-kinase/Akt signaling pathway." Chinese Medical Journal 127.5 (2014): 929-936.
Pubmed: 24571890
DOI: NA
Research Highlights
Hatamabadi, Dara. et al. "Synthesis and Radiolabeling of Glu-Urea-Lys with 99mTc-Tricarbonyl-Imidazole-Bathophenanthroline Disulfonate Chelation System and Biological Evaluation as Prostate-Specific Membrane Antigen Inhibitor." Cancer biotherapy & radiopharmaceuticals, 2023.
This article investigates the impact of climate change on global agriculture and food security. It begins by outlining prevalent difficulties encountered by small-scale farmers, especially in developing nations, such as droughts, floods, and soil deterioration. The abstract subsequently examines potential adaptation methods, including the utilization of climate-resistant crop varieties and advanced water management techniques. Lastly, it emphasizes the significance of international collaboration and investment in sustainable agriculture to mitigate the consequences of climate change and ensure food security for the entire population.
Hatamabadi, Dara. et al. "Synthesis and Radiolabeling of Glu-Urea-Lys with 99mTc-Tricarbonyl-Imidazole-Bathophenanthroline Disulfonate Chelation System and Biological Evaluation as Prostate-Specific Membrane Antigen Inhibitor." Cancer biotherapy & radiopharmaceuticals, 2023.
Pubmed:
37578479
DOI:
10.1089/cbr.2023.0024
Soler-Blasco, Raquel. et al. "Influence of genetic polymorphisms on arsenic methylation efficiency during pregnancy: Evidence from a Spanish birth cohort." The Science of the total environment, 2023.
Inorganic arsenic (iAs) is a commonly found toxic metalloid with known effects on human health. The metabolism and toxicity of iAs are influenced by variations in genes such as AS3MT and GSTO2. Despite this, there is a lack of research on the impact of genetic polymorphisms during pregnancy. The objective of this study was to investigate the relationship between AS3MT, GSTO2, N6AMT1, MTHFR, MTR, FTCD, CBS, and FOLH1 polymorphisms and iAs methylation efficiency in pregnant women.
Soler-Blasco, Raquel. et al. "Influence of genetic polymorphisms on arsenic methylation efficiency during pregnancy: Evidence from a Spanish birth cohort." The Science of the total environment, 2023.
Pubmed:
37495132
DOI:
10.1016/j.scitotenv.2023.165740
