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    mProX™ Human ESR1 Stable Cell Line

    [CAT#: S01YF-1123-KX95]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Nuclear Receptor

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    Host Cell Type:
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    Product Information

    Target Protein
    ESR1
    Target Family
    Estrogen Receptor
    Target Protein Species
    Human
    Host Cell Type
    SUM-44; CHO-K1; HEK293
    Target Classification
    Nuclear Receptor
    Target Research Area
    Cancer Research; Reproductive Research
    Related Diseases
    Estrogen Resistance; Breast Cancer
    Gene ID
    2099
    UniProt ID
    P03372

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    NR3A1, or estrogen receptor alpha, is one of the two primary forms of estrogen receptors. The human gene ESR1 (EStrogen Receptor 1) encodes ERα. To varied degrees, ERα contributes to the physiological development and operation of several organ systems, including as the reproductive, central nervous, skeletal, and cardiovascular systems. As a result, ERα is widely expressed in many different parts of the body, such as the pituitary gland, uterus, ovary, male reproductive organs, bone, heart, hypothalamus, liver, lung, kidney, spleen, and adipose tissue. Animal models devoid of functioning ERα genes, like the ERα knockout mouse (ERKO), cause disturbances in the development and function of certain tissues, offering an initial comprehension of ERα function at particular target organs. The customized ESR1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human ESR1 Stable Cell Line (S01YF-1123-KX95). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Thomas (Verified Customer)

    Does the ESR1 cell line have a tag? Where is the tag? Mar 08 2023

    chat Sherry Smith (Creative Biolabs Scientific Support)

    We can customize tags to suit your needs. Mar 08 2023

    chat Karen (Verified Customer)

    What's the significance of ESR1 mutation? Dec 25 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    The ESR1 mutation is a common resistance mutation. Resistance mutations are ways that cancer develops after being treated with certain cancer therapies. Dec 25 2022

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    • Magic™ Human ESR1 (D538G) HEK293 Cell Line (CAT#: S01YF-0324-KX224)
    • mProX™ Human ESR1 Stable Cell Line (CAT#: S01YF-1123-KX95)
    • Magic™ Human ESR1 HEK293 Cell Line (CAT#: S01YF-0324-KX223)
    • Magic™ Human ESR1 (Y537S) HEK293 Cell Line (CAT#: S01YF-0324-KX226)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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