mProX™ Human DCLK2 Stable Cell Line
[CAT#: S01YF-1123-KX212]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
DCLK2
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Reproductive Research
Related Diseases
Lissencephaly and Band Heterotopia
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
A member of the doublecortin family and the protein kinase superfamily is encoded by this gene. The protein that this gene encodes has three main domains: a Cterminal serine/threonine protein kinase domain that resembles Ca2+/calmodulindependent protein kinase significantly, two Nterminal doublecortin domains that bind microtubules and control microtubule polymerization, and a serine/prolinerich domain that mediates multiple protein-protein interactions between the doublecortin and protein kinase domains. The encoded protein's ability to microtubule polymerize is unrelated to its protein kinase activity. According to mouse research, this gene, along with a family member called DCX, is involved in the creation of hippocampus organization. Their absence leads to a severe epileptic phenotype and death, which is similar to what is seen in lissencephaly patients who are human. The customized DCLK2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Jason
Its reliability and user-friendly design have simplified the process of DCLK2 drug discovery in our lab.
Aug 17 2023
Verified Customer
Laura
I have used the DCLK2 cell line extensively in my studies, and it consistently delivered outstanding performance.
Jan 14 2022
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
