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  • mProX™ Human CHRNA7/ric3 Stable Cell Line

    [CAT#: S01YF-1123-KX79]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Product Information

    Target Protein
    CHRNA7/ric3
    Target Family
    Acetylcholine Nicotinic Channel
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Epilepsy
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Initially, a P50 auditory-evoked potential deficit-a neurophysiological characteristic frequently observed in schizophrenia-was associated with the alpha7 nicotinic receptor (CHRNA7). The genetic marker is found at chromosome 15q13-14, a linkage that results from nine European-American high-density psychotic families that are impacted many times. Subsequent analysis and validation of the findings from the previous inquiry revealed a significant genotype-wise disequilibrium at D15S165. This polymorphic simple sequence marker is located 120 kb away from the coding area of CHRNA7. The human gene is a portion of a duplicate cassette of expressed sequences that are almost next to one another. Four new exons and six exons that replicate exons 5-10 of the full-length CHRNA7 make up the expressed sequence. The customized CHRNA7/ric3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Deborah

    The performance of the CHRNA7/ric3 cell line was consistent, and the company's support team was responsive and helpful throughout the process. Sep 19 2021

    chat Verified Customer

    chat James

    I have tested the CHRNA7/ric3 cell line from Creative Biolabs as one of the most reliable and versatile options available. Mar 18 2023

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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