mProX™ Human CHRNA4/CHRNA6/CHRNB2 Stable Cell Line

[CAT#: S01YF-1123-KX77]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Ion Channel Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

CHRNA4/CHRNA6/CHRNB2

Target Family

Acetylcholine Nicotinic Channel

Target Protein Species

Human

Host Cell Type

STC-1; CHO-K1; HEK293

Target Classification

Ion Channel Cell Lines

Target Research Area

CNS Research

Related Diseases

Epilepsy

Gene ID

1137

UniProt ID

P43681

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Receptor polypeptides known as nicotinic acetylcholine receptors, or nAChRs, react to the neurotransmitter acetylcholine. Substances like the agonist nicotine also have an effect on nicotinic receptors. They are present in many different tissues of numerous creatures, including muscle and the peripheral and central nervous systems. They are the main receptor in the muscle at the neuromuscular junction, where motor neuron and muscle communicate to control muscle contraction. They serve two purposes in the peripheral nervous system: (1) they are the receptors on skeletal muscle that receive the release of acetylcholine, which signals the contraction of muscles; and (2) they are the outgoing signals from the presynaptic to the postsynaptic cells within the sympathetic and parasympathetic nervous systems. nAChRs control inflammatory processes in the immune system and communicate via unique intracellular pathways. The customized CHRNA4/CHRNA6/CHRNB2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Donna

I recently purchased the CHRNA4/CHRNA6/CHRNB2 cell line, and it has exceeded my expectations. Jan 29 2023

chat Verified Customer

chat Jessica

We are delighted with the versatility and efficiency of CHRNA4/CHRNA6/CHRNB2 cell line as a research tool. Sep 24 2022

chat Verified Customer

FAQ

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