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  • mProX™ Human CHRNA3/CHRNB4 Stable Cell Line

    [CAT#: S01YF-1123-KX76]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    CHRNA3/CHRNB4
    Target Family
    Acetylcholine Nicotinic Channel
    Target Protein Species
    Human
    Host Cell Type
    HBO; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Bladder Dysfunction; Autonomic
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The nAChR gene cluster, located on chromosome 15q25.1, is a member of the ligand-gated ion channel superfamily. It is widely distributed in the brain and mediates fast cholinergic synaptic transmission by binding the ligands nicotine and acetylcholine. This process also involves activating downstream signaling networks that support angiogenesis, migration, and cell proliferation. Additionally, nAChRs have been linked to smoking habits, nicotine dependence, and an increased risk of lung cancer and chronic obstructive pulmonary disease (COPD). The customized CHRNA3/CHRNB4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat William

    The convenience of the CHRNA3/CHRNB4 cell line has significantly streamlined my workflow. Jul 28 2020

    chat Verified Customer

    chat Amanda

    The CHRNA3/CHRNB4 cell line is of superior quality, and I am confident in its reliability. Jan 19 2020

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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