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  • mProX™ Human BDKRB1 Stable Cell Line

    [CAT#: S01YF-0923-PY24]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    BDKRB1
    Target Family
    Bradykinin Family
    Target Protein Species
    Mouse
    Host Cell Type
    RAW264.7;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Immunology Research;Digestive and Renal Research
    Related Diseases
    End Stage Renal Disease;Covid-19
    Gene ID
    Mouse: 12061
    UniProt ID
    Mouse: Q61125

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Bradykinin Receptor B1 (BDKRB1) has been a focal point in numerous scientific studies due to its role in various physiological processes. One of the intriguing aspects of BDKRB1 is its involvement in the modulation of inflammatory responses. It has been identified that BDKRB1 plays a crucial role in mediating inflammation, especially in conditions where there is tissue injury or infection. This receptor is upregulated during these inflammatory conditions, making it a potential therapeutic target for diseases characterized by inflammation. Moreover, studies have also highlighted the potential role of BDKRB1 in vascular functions, suggesting its involvement in blood pressure regulation. The interaction between BDKRB1 and other systems, such as the angiotensin system, has been explored to understand the intricate balance of vasodilation and vasoconstriction in cardiovascular health. Furthermore, the genetic polymorphisms associated with BDKRB1 have been investigated to understand their potential impact on drug responses, especially in the context of antihypertensive therapies. Overall, the application of BDKRB1 in scientific research spans from understanding basic physiological processes to exploring therapeutic interventions for various diseases.

    Protocols

    Please visit our protocols page.

    Customer Reviews

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    FAQ

    chat Kimberly (Verified Customer)

    Are there any known associations between BDKRB1 and diseases or disorders? Jun 14 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, for instance, the BDKRB1 rs12050217 G allele has been associated with protection against the advanced stage of diabetic retinopathy in T2DM patients. Jun 14 2023

    chat Rebecca (Verified Customer)

    How is BDKRB1 related to membrane protein cell lines? Feb 15 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    BDKRB1 is a membrane protein, and its expression and function can be studied using cell lines that express this receptor. These cell lines can help in understanding the receptor's role in inflammation and other cellular processes. Feb 15 2021
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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