mProX™ Human AVPR1B Stable Cell Line
[CAT#: S01YF-0923-KX56]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
AVPR1B
Target Family
Vasopressin and Oxytocin Family
Target Protein Species
Human
Host Cell Type
HepG2; CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cancer Research; CNS Research; Digestive and Renal Research
Related Diseases
Bronchial Neuroendocrine Tumor; Acth-Independent Macronodular Adrenal Hyperplasia
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Vasopressin (AVP), a neurohypophyseal peptide, plays a variety of physiological roles, including platelet aggregation, activation of liver glycogenolysis, contraction of vascular smooth muscle cells, and antidiuresis. The three subtypes of G protein-coupled AVP receptors-V1a, V1b, and V2-encoded by the human AVPR1A, AVPR1B, and AVPR2 genes, respectively, are G protein-coupled AVP receptors. Pituitary corticotropes are the principal source of type 1b receptor expression, which mediates the stimulatory effects of AVP on ACTH production. Nevertheless, AVPR1B expression has been noted in numerous brain regions and peripheral organs, and recent research has shown that AVP can stimulate the release of glucagon and insulin from isolated rodent pancreatic islets via the V1b receptor. The customized AVPR1B stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Cecil
This cell line is perfect for my experiments.
Apr 22 2023
Verified Customer
Wordsworth
Professional products and professional services.
Jun 02 2023
Verified Customer
FAQ
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