mProX™ Human ADORA2A Stable Cell Line

Product Information

Target Protein

ADORA2A

Target Family

Adenosine Family

Target Protein Species

Human

Host Cell Type

K562;KCL22;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research

Related Diseases

Acute Encephalopathy With Biphasic Seizures And Late Reduced Diffusion;Basal Ganglia Disease

Gene ID

Human: 135

UniProt ID

Human: P29274

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Adenosine receptor A2A (ADORA2A) has been the subject of various scientific investigations, especially in relation to neurological and oncological conditions. For instance, certain genetic variants of ADORA2A have been explored as potential risk factors for Parkinson's disease, although the results suggest that it might not be among the major risk factors. In the realm of oncology, ADORA2A antisense RNA 1 has been identified as having an oncogenic effect in chronic myeloid leukemia (CML), suggesting its potential as a therapeutic target source. Moreover, the influence of caffeine on exercise performance, which is modulated by ADORA2A genotypes, has been studied, revealing that the ergogenic effects of caffeine may vary based on these genotypes. The diverse roles of ADORA2A in various physiological and pathological processes highlight its significance in scientific research and its potential implications for therapeutic interventions.

Protocols

Please visit our protocols page.

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FAQ

chat Sharon (Verified Customer)

What is the role of ADORA2A in DNA repair and genomic integrity? Dec 02 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

ADORA2A is involved in various cellular processes, including DNA repair. Ensuring the stability of this protein in cell lines is crucial for maintaining genomic integrity. Dec 02 2022

chat Ronald (Verified Customer)

How do ADORA2A stabilized cell lines compare to other commonly used cell lines in research? Feb 09 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

ADORA2A stabilized cell lines offer unique insights specific to their function. However, like other cell lines, their effectiveness depends on the accuracy of the stabilization process. Feb 09 2021

mProX™ Human ADORA2A Stable Cell Line

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Protocols

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