mProX™ Human ADGRE1 Stable Cell Line
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
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Published Data
Fig.1 High EMR1 expression in colon cancer cells.
Western blot examination showed that after 48 h of CM treatment, relative EMR1 protein expression was found in both myeloid-derived HCT15 and Caco2 cancer cells.
Ref: Akter, Rokeya, et al. "EMR1/ADGRE1 Expression in Cancer Cells Upregulated by Tumor-Associated Macrophages Is Related to Poor Prognosis in Colorectal Cancer." Biomedicines 10.12 (2022): 3121.
Pubmed: 36551877
DOI: 10.3390/biomedicines10123121
Research Highlights
These three hub genes, ADGRE1, CCL18, and LILRA6, may have a role in the development of PCPG and could be used as novel treatment targets and potential biomarkers.
Chen, C. X., et al. Identification of vital prognostic genes related to tumor microenvironment in pheochromocytoma and paraganglioma based on weighted gene co-expression network analysis. Aging (Albany NY). 2021, 13(7), 9976.
Pubmed:
33795528
DOI:
10.18632/aging.202754
Worldwide, non-alcoholic steatohepatitis (NASH), which is directly related to obesity, is a health concern.
Kim, M. B., et al. Sugar kelp (Saccharina latissima) inhibits hepatic inflammation and fibrosis in a mouse model of diet-induced nonalcoholic steatohepatitis. The Journal of Nutritional Biochemistry. 2021, 97, 108799.
Pubmed:
34119629
DOI:
10.1016/j.jnutbio.2021.108799
Multiple physiological processes, including the immune system, are impacted by malnutrition. The exact mechanism by which starvation lowers immune responses is still unknown.
Nakayama, K., et al. Activation of macrophages mediates dietary restriction-induced splenic involution. Life Sciences. 2022, 310, 121068.
Pubmed:
36243119
DOI:
10.1016/j.lfs.2022.121068