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    mProX™ Human ADGRB2 Stable Cell Line

    [CAT#: S01YF-0223-KX2]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    ADGRB2
    Target Family
    Orphan Family
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Cardiovascular Research; CNS Research; Orphan Receptor Research
    Related Diseases
    ibratory Urticaria; Polymicrogyria; Bilateral Frontoparietal
    Gene ID
    576
    UniProt ID
    O60241

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The human body contains several adhesion GPCRs (aGPCRs), many of which have loss-of-function mutations that are linked to disease. One of three ADGRB sub-family receptors known as Brain-specific Angiogenesis Inhibitors 1-3 (BAI1-3), BAI2 (ADGRB2) is one of these receptors. The brain tissue has the highest levels of expression for these receptors, and studies have revealed that BAI1 (ADGRB1) and BAI3 (ADGRB3) play significant roles at synapses. Less is currently understood regarding BAI2's function. Mice missing BAI2 showed greater hippocampus neurogenesis and resistance to learned helplessness behavior but no obvious impairments. The customized ADGRB2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    There are currently no Customer reviews or questions for mProX™ Human ADGRB2 Stable Cell Line (S01YF-0223-KX2). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Julie (Verified Customer)

    What assays can the ADGRB2 Stable Cell Line be used for? Mar 15 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    This cell line is customized for drug discovery, and it also can be used in ELISA and Western Blots. Mar 15 2022

    chat Gary (Verified Customer)

    The cell line can be used for quantitative measurements? Jan 19 2023

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Through the creation of a standard curve with a positive control, it can be used for quantitative measurements. Jan 19 2023

    Related Products by Target
    • mProX™ Human ADGRB2 Stable Cell Line (CAT#: S01YF-0223-KX2)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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