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    mProX™ Human ADGRB1 Stable Cell Line

    [CAT#: S01YF-0223-KX1]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    ADGRB1
    Target Family
    Orphan Family
    Target Protein Species
    Human
    Host Cell Type
    MB; CHO-K1; HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Cancer Research; Cardiovascular Research; Infectious Research; Orphan Receptor Research
    Related Diseases
    Glioblastoma; Carey-Fineman-Ziter Syndrome
    Gene ID
    575
    UniProt ID
    O14514

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The adhesion GPCR BAI1/ADGRB1 is crucial for mediating phagocytosis, inhibiting angiogenesis, and preventing the growth of brain tumors. Along with regulating the growth of excitatory synapse and dendritic spines, BAI1 interacts with a number of proteins that are important for autism. According to studies, overexpressing BAI1 causes dendrites to retract whereas underexpressing BAI1 causes dendrites to grow more immature and unstable. Continuous dendritic morphological changes and proper PSD-95 (post-synaptic density 95) function are crucial for learning and memory and are frequently affected in neurological and neurodevelopmental conditions that are characterized by hampered social interaction, communication difficulties, and an increase in repetitive behaviors. The customized ADGRB1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human ADGRB1 Stable Cell Line (S01YF-0223-KX1). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Gary (Verified Customer)

    Q: Does this cell line overexpress full-length ADGRB1? Mar 12 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    A: The cell line is a customized cell line. You can choose a suitable host cell to overexpress, KO or KD. Mar 12 2022

    chat Shirley (Verified Customer)

    Q: What is the QC for Human ADGRB1 Stable Cell Line? Jan 27 2020

    chat Sherry Smith (Creative Biolabs Scientific Support)

    A: Before shipping, the cell line is examined for bacterial and mycoplasma contamination. The QC also includes flow cytometry to verify the surface expression of ADGRB1 at the protein level and qPCR to verify the engineering results at the mRNA level. Please contact us for specific information. Jan 27 2020

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    • mProX™ Human ADGRB1 Stable Cell Line (CAT#: S01YF-0223-KX1)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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