Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. ABCG2
  3. mProX™ Human ABCG2 Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP Transporter Cell Lines,Drug Discovery Tools
    Family stable cell lines ABC Transporter Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human ABCG2 Stable Cell Line

    [CAT#: S01YF-1123-KX116]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Transporter Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-0922-KX1555 Magic™ Human ABCG2 in Vitro Drug screening assay Human Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )

    Product Information

    Target Protein
    ABCG2
    Target Family
    ABC Transporter
    Target Protein Species
    Human
    Host Cell Type
    NSCLC; CHO-K1; HEK293
    Target Classification
    Transporter Cell Lines
    Target Research Area
    Cancer Research; Metabolic Research
    Related Diseases
    Uric Acid Concentration; Blood Group
    Gene ID
    9429
    UniProt ID
    Q9UNQ0

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The ATP-binding cassette gene family, which includes the ABCG2 gene, offers instructions for producing proteins that carry chemicals across cell membranes. The ABCG2 protein aids in the intestines' release (secretion) of urate into the urine. It functions as an antioxidant in the bloodstream, shielding cells from the corrosive effects of unstable molecules known as free radicals. The kidneys and, to a lesser extent, the intestines control the amounts of urea. Certain medications are also transported out of cells via the ABCG2 protein. This protein, for instance, removes certain chemotherapy medications from tissues and organs. These medications' transportation enables both their intended effects and bodily elimination. The customized ABCG2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Ashley

    The ABCG2 cell line is a good product for general routine use from Creative Biolabs. Sep 01 2022

    chat Verified Customer

    chat Gary

    I recently purchased the human ABCG2 cell line, and it has been a valuable tool in my laboratory work for drug screening. Jul 06 2022

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Related Products by Target
    • mProX™ Human ABCG2 Stable Cell Line (CAT#: S01YF-1123-KX116)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare