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    mProX™ Human ABCC2 Stable Cell Line

    [CAT#: S01YF-1123-KX117]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Transporter Cell Lines

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    Host Cell Type:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-0922-KX1556 Magic™ Human ABCC2 in Vitro Drug screening assay Human Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )

    Product Information

    Target Protein
    ABCC2
    Target Family
    ABC Transporter
    Target Protein Species
    Human
    Host Cell Type
    CNE2; CHO-K1; HEK293
    Target Classification
    Transporter Cell Lines
    Target Research Area
    Cancer Research; Metabolic Research
    Related Diseases
    Dubin-Johnson Syndrome; Pseudoxanthoma Elasticum
    Gene ID
    1244
    UniProt ID
    Q92887

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Multidrug resistance protein 2 (MRP2) is a protein that is produced by the ABCC2 gene. This protein is a member of a family of multidrug resistance proteins that are involved in the exocytosis of drugs. For instance, MRP2 participates in drug metabolism by removing specific medications from tissues and organs. Additionally, MRP2 moves bilirubin-a chemical produced by the liver-from liver cells into bile, the digestive fluid produced by the liver. The breakdown of aged red blood cells produces bilirubin, which has an orange-yellow color. MRP2 is mostly present in the outer membrane that envelops liver cells; traces of it are also present in the kidneys, gut, and placenta. The customized ABCC2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Ashley

    The ABCC2 cell line design is well-optimized, and the provided documentation is comprehensive. Apr 12 2021

    chat Verified Customer

    chat Stephanie

    I would recommend this product to anyone who wants to research ABCC2. Nov 01 2021

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Related Products by Target
    • mProX™ Human ABCC2 Stable Cell Line (CAT#: S01YF-1123-KX117)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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