Human NECTIN4 Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX886]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human NECTIN4 for Lentivirus Production.
Target Protein
NECTIN4
Target Protein Species
Human
Target Classification
Immune Checkpoint
Target Research Area
Metabolic Research
Related Diseases
Ectodermal Dysplasia-Syndactyly Syndrome; Measles
Target Family
Immune Checkpoint
Vector
pLV
Vector Type
Lentiviral Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
CMV, SV40, EF1a, CAG etc.
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Fluorescent Markers
EGFP, mCherry etc.
Selection Markers
Puromycin, Hygromycin, Neomycin, Blasticidin etc.
Product Properties
Applications
Lentivirus Production
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Nectin cell adhesion molecule 4
Introduction
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Alternative Names
NECTIN4; LNIR; PRR4; EDSS1; PVRL4; nectin-4; nectin-4; Ig superfamily receptor LNIR; nectin 4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; Nectin cell adhesion molecule 4
Gene ID
UniProt ID
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