NECTIN4
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
| Full Name | Nectin cell adhesion molecule 4 |
| Gene ID | Human: 81607 Mouse: 71740 Rat: 498281 Monkey: 719843 |
| UniProt ID | Human: Q96NY8 Mouse: Q8R007 Rat: D3ZET1 Monkey: A0A5F7ZXJ3 |
| Alternative Names | NECTIN4; LNIR; PRR4; EDSS1; PVRL4; nectin-4; nectin-4; Ig superfamily receptor LNIR; nectin 4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; Nectin cell adhesion molecule 4 |
Product List
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Magic™ Human NECTIN4 4T1 Cell Line
[CAT#: S01YF-0324-KX19]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: 4T1 Assay Types: Functional assay and biological assay
Magic™ Human NECTIN4 B16F10 Cell Line
[CAT#: S01YF-0123-KX82]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: B16F10 Assay Types: Drug screening and biological assays
Magic™ Human NECTIN4 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX174]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human NECTIN4 CT26 Cell Line
[CAT#: S01YF-0324-KX62]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
Magic™ Human NECTIN4 EMT6 Cell Line
[CAT#: S01YF-0324-KX75]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: EMT6 Assay Types: Functional assay and biological assay
Magic™ Human NECTIN4 H22 Cell Line
[CAT#: S01YF-0324-KX23]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: H22 Assay Types: Functional assay and biological assay
Magic™ Human NECTIN4 HEK293T Cell Line
[CAT#: S01YF-0123-KX175]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human NECTIN4 MC-38 Cell Line
[CAT#: S01YF-0324-KX125]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human NECTIN4 PC3 Cell Line
[CAT#: S01YF-0123-KX52]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NECTIN4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: PC3 Assay Types: Drug screening and biological assays
mProX™ Human NECTIN4 Stable Cell Line
[CAT#: S01YF-1023-PY200]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Mel1617;SK-MEL-28 Assay Types: Biological assays
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