Human HTR1A Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX292]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order LNP-mRNA encoding human HTR1A.
Target Protein
HTR1A
Target Protein Species
Human
Target Classificationp
GPCR
Target Research Area
CNS Research
Related Diseases
Periodic Fever; Menstrual Cycle-Dependent; Generalized Anxiety Disorder
Target Family
Serotonin
RNA Type
LNP-mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
LNP Encapsulation mRNA
LNP Formulation
Conventional and custom formulation with helper lipid, lonizable lipid, cholesterol and lipid-anchored PEG
Buffer
Tris buffer or PBS
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Encapsulation Efficiency
PASS
mRNA Transfection Efficiency
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Blue Ice
Storage
Aliquot and store at 2-8°C for long term.
Target
Full Name
5-hydroxytryptamine receptor 1A
Introduction
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.
Alternative Names
G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1;5-hydroxytryptamine receptor 1A;5-HT1a receptor;5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled;guanine nucleotide-binding regulatory protein-coupled receptor;Serotonin receptor 1A;HTR1A
Gene ID
UniProt ID
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