Human AGTR1 Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1037]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human AGTR1 for In Vitro Transcription.
Target Protein
AGTR1
Target Protein Species
Human
Target Classification
GPCR
Target Research Area
Cardiovascular Research; Digestive and Renal Research; Infectious Research
Related Diseases
Renal Tubular Dysgenesis; Hypertension
Target Family
Angiotensin receptor
Vector
pIVT
Vector Type
In Vitro Transcription (IVT) Vector
Note
Resistance
KanR
Growth Temperature
37°C
Relevant Promoters
T7
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
In Vitro Transcription
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Angiotensin II receptor type 1
Introduction
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants.
Alternative Names
AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B; type-1B angiotensin II receptor; AGTR1; Angiotensin II receptor type 1
Gene ID
UniProt ID
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