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AGTR1

A powerful vasopressor hormone, angiotensin II is also the main factor controlling the release of aldosterone. It is a crucial factor in the cardiovascular system's volume and blood pressure regulation. It operates on at least two different receptor types. The diseases Renal Tubular Dysgenesis and Essential Hypertension are linked to AGTR1. Thromboxane signaling through the TP receptor and the mitochondrial immune response to SARS-CoV-2 are two of its associated mechanisms. Angiotensin type II receptor activity and G protein-coupled receptor activity are two Gene Ontology (GO) annotations connected to this gene.

Full Name Angiotensin II receptor type 1
Gene ID Human: 185
Mouse: 11607
Rat: 24180
Monkey: 712773
UniProt ID Human: P30556
Mouse: P29754
Rat: P25095
Monkey: A0A2K6TZ71
Alternative Names AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B; type-1B angiotensin II receptor; AGTR1; Angiotensin II receptor type 1

Product List

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Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: AGTR1 Target Family: Angiotensin Receptor Target Protein Species: Dog Host Cell Type: CHO-K1 Assay Types: Radioligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: β-Arrestin Assay
Product Category:
Membranes
Target Protein: AT1 Target Family: Angiotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Product Category:
Membranes
Target Protein: AT1 Target Family: Angiotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Product Category:
Membranes
Target Protein: AT1 Target Family: Angiotensin Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Product Category:
Membranes
Target Protein: AT1 Target Family: Angiotensin Target Protein Species: Human Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Hydroxycarboxylic acid receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Angiotensin Receptors Target Protein Species: Human
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: AT1 Target Family: Angiotensin Receptor Target Protein Species: Rat Assay Types: Radioligand Binding Assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: AGTR1 Target Family: Angiotensin Receptor Target Protein Species: Rat Host Cell Type: HEK293-Ga15 Assay Types: Calcium Assay; Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: AGTR1 Target Family: Anaphylatoxin Family Target Protein Species: Human Host Cell Type: HepG2;Huh7;CHO-K1;HEK293 Assay Types: Biological assays
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