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WNK4

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

Full Name WNK lysine deficient protein kinase 4
Gene ID Human: 65266 Mouse: 69847 Rat: 287715 Monkey: 707820
UniProt ID Human: Q96J92 Mouse: Q80UE6 Rat: Q7TPK6
Alternative Names PHA2B; PRKWNK4;serine/threonine-protein kinase WNK4;protein kinase lysine-deficient 4;protein kinase with no lysine 4

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;DLD-1
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