TYK2
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.
Full Name | tyrosine kinase 2 |
Gene ID | Human: 7297 Mouse: 54721 Rat: 100361294 Monkey: 574130 |
UniProt ID | Human: P29597 Mouse: Q9R117 Rat: D3ZD03 |
Alternative Names | JTK1; IMD35;non-receptor tyrosine-protein kinase TYK2 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Jurkat