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TYK2

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.

Full Name tyrosine kinase 2
Gene ID Human: 7297 Mouse: 54721 Rat: 100361294 Monkey: 574130
UniProt ID Human: P29597 Mouse: Q9R117 Rat: D3ZD03
Alternative Names JTK1; IMD35;non-receptor tyrosine-protein kinase TYK2

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Magic™ Human TYK2 Assay [CAT#: S01YF-1222-KX521]

Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: TYK2 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Jurkat Assay Types: Biological assays
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