TNFRSF8
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
| Full Name | TNF receptor superfamily member 8 |
| Gene ID | Human: 943 Mouse: 21941 Rat: 25069 Monkey: 722773 |
| UniProt ID | Human: P28908 Mouse: Q60846 Rat: P97525 Monkey: F7GUT8 |
| Alternative Names | TNFRSF8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; cytokine receptor CD30; lymphocyte activation antigen CD30; TNF receptor superfamily member 8 |
Product List
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Magic™ Human TNFRSF8 CHO-S Cell Line
[CAT#: S01YF-0424-KX19]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF8 Target Family: Oncology Target Protein Species: Human Host Cell Type: CHO-S Assay Types: Functional assay
mProX™ Human TNFRSF8 Stable Cell Line
[CAT#: S01YF-1023-PY241]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Oncology Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;SU-DHL-1
Magic™ Human TNFRSF8 HT1080 Cell Line
[CAT#: S01YF-0123-KX340]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF8 Target Family: Oncology Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HT1080 Assay Types: Drug screening and biological assays
Magic™ Human TNFRSF8 HEK293T Cell Line
[CAT#: S01YF-0123-KX332]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF8 Target Family: Oncology Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
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