TNFRSF4
This gene encodes a protein that belongs to the TNF-receptor superfamily. It has been demonstrated that this receptor interacts with the adaptor proteins TRAF2 and TRAF5 to activate NF-kappaB. According to mouse knockout experiments, this receptor reduces apoptosis by promoting the expression of the apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL. The deletion studies further revealed that this receptor plays a part in CD4+ T cell response, B cell proliferation, and differentiation that is dependent on T cells.
| Full Name | TNF receptor superfamily member 4 |
| Gene ID | Human: 7293 Mouse: 22163 Rat: 25572 Monkey: 699674 |
| UniProt ID | Human: P43489 Mouse: P47741 Rat: P15725 Monkey: A0A5F8ALC1 |
| Alternative Names | TNFRSF4; OX40; ACT35; CD134; IMD16; TXGP1L; tumor necrosis factor receptor superfamily member 4; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; lymphoid activation antigene ACT35; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4 |
Product List
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Magic™ Cyno TNFRSF4 HEK293T Cell Line
[CAT#: S01YF-0123-KX316]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF4 Target Family: Immune Checkpoint Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human OX40 (TNFRSF4) Stable Cell Line
[CAT#: S01YF-1023-PY164]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;A549;SPC-A1;HFL1;Jurkat;Raji Assay Types: Biological assays
Magic™ Human TNFRSF4 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX157]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Human TNFRSF4 HEK293T Cell Line
[CAT#: S01YF-0123-KX317]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human TNFRSF4 HT1080 Cell Line
[CAT#: S01YF-0123-KX352]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HT1080 Assay Types: Drug screening and biological assays
Magic™ Human TNFRSF4 HT1080 Cell Line with NFkb-Luc2 Reporter
[CAT#: S01YF-1222-KX893]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNFRSF4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HT1080 Assay Types: Drug screening and biological assays
Magic™ Human TNFRSF4 U2OS Cell Line, Checkpoint Assay
[CAT#: S01YF-0822-KX752]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OX40 Target Family: Tumor Necrosis Factor Receptor Superfamily Receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Checkpoint Assay
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