TNFRSF4
This gene encodes a protein that belongs to the TNF-receptor superfamily. It has been demonstrated that this receptor interacts with the adaptor proteins TRAF2 and TRAF5 to activate NF-kappaB. According to mouse knockout experiments, this receptor reduces apoptosis by promoting the expression of the apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL. The deletion studies further revealed that this receptor plays a part in CD4+ T cell response, B cell proliferation, and differentiation that is dependent on T cells.
| Full Name | TNF receptor superfamily member 4 |
| Gene ID | Human: 7293 Mouse: 22163 Rat: 25572 Monkey: 699674 |
| UniProt ID | Human: P43489 Mouse: P47741 Rat: P15725 Monkey: A0A5F8ALC1 |
| Alternative Names | TNFRSF4; OX40; ACT35; CD134; IMD16; TXGP1L; tumor necrosis factor receptor superfamily member 4; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; lymphoid activation antigene ACT35; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4 |
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Magic™ Human OX40 (TNFRSF4) Stable Cell Line
[CAT#: S01YF-1023-PY164]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;A549;SPC-A1;HFL1;Jurkat;Raji
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